Dermatology - diseases of the skin

Herpes Skin and Mucosal


Herpes skin and mucosal

There are more than 80 types of herpes viruses. Herpes sore all life on planet Earth, in addition to fungi and some species of algae. 80 types of herpes, human diseases can be caused by a 9. The herpes virus have the specificity, i.e. the person may not get cold sores, which suffer from the pig, and the pig can’t get from a man. The exception is the simian herpes virus.

About 90% of the population infected with herpes. 5% of the population have symptoms of herpes, and the rest of asymptomatic carriage. Primary infection with a virus of a simple herpes usually occurs in early childhood, but sometimes later. Most children signs of infection are limited to a single rash around the mouth. Occasionally develop acute stomatitis with a pronounced change in the General condition. Herpes can “pop out” and on the lips and on the nose, and on the body, and on the genitals (genital herpes).

Pathogen herpes on lips, herpes and sex herpesis herpes simplex virus (HSV).

Physico-chemical properties of herpes virus: killed when exposed to temperatures at 500C for 30 minutes At a 37.50C for 20 hours. Can forever be maintained at a temperature of -700C. withstand lyophilization. Resistant to successive freezing and thawing, exposure to ultrasonic radiation. In the saliva in the storage interval to 30 minutes, the virus retains its viability. On wet sterile medical cotton and gauze during the whole time of drying (up to 6 hours). On average, the virus is viable in the environment at normal temperature and humidity for 24 hours.

The above is evidence of the death of the virus are in vitro or laboratory conditions. To kill the virus inside the body using existing techniques is unrealistic (hyperemia, the removal of the nerve ganglia, the destruction of the ganglia by the introduction of chemicals, ozonation of blood, etc.). Attempts such treatment may lead to profound disability of the patient or even his death.

Inactivated herpes simplex virus under the action of x-rays and ultraviolet rays, alcohol, organic solvents, phenol, formalin, proteolytic enzymes, bile, common disinfectants.

The infection is transmitted primarily by contact (through kissing, sharing eating utensils, shared towel during sexual contact), as well as airborne, and possible transplacental route of infection (from mother to fetus during childbirth).

The virus gets into the body through the skin or mucous membranes, further falls in regional lymph nodes, blood and internal organs. Spreading the virus through the blood and the nerve trunks, the way it is in the nerve ganglia, the virus remains for a lifetime, periodically causing exacerbation of depressed immunity, by overheating or overcooling, in stressful situations, in a number of diseases (eg. for pneumonia, influenza, malaria, etc.), gastrointestinal disorders, while taking some medications, after surgery.

There is a risk of herpes virus following bodies:

  1. leather
  2. the eye (keratitis, conjunctivitis);
  3. mucous membranes (face and genitals);
  4. central nervous system (meningitis, encephalitis).

Route of infection with herpes:

sexual, airborne (very rarely) when the primary infection, the virus can be transmitted through the placenta.

Herpes Symptoms

Herpes SymptomsOn the skin or mucous for a few days before the rash appears a burning sensation, tingling, redness, everything is possible with the worsening of the General condition, then there are thin-walled vesicles with a red rim on periferie. These vesicles (bubbles) are often clustered together, first they are transparent, but quickly become turbid (due to the mixing with blood, pus), they quickly opened with the formation of crusts after falling which scarring remains. on mucous genitals rashes smaller, there is also pain, burning, itching, men’s items are located in the foreskin, the glans and the shaft of the penis, in women affects large and small lips, crotch, thighs and cervix.

Usually after 6-8 days the disease is. People are contagious for several days before the appearance of bubbles and 7-8 days after.

During exacerbation herpes, and type 1 and 2 you should refrain from sexual contact.

With persistent and frequent exacerbation herpes necessary to exclude HIV infection.

Diagnosis of herpes

Usually enough examination, but the following methods are used:

  • virological methods detection of the virus;
  • polymerase chain reaction (PCR);
  • antibodies to the virus
  • cytomorphological methods.

Treatment of herpes

Treatment of herpesWith frequent exacerbations of herpes (from 1 times a month) conduct specific herpes vaccination (the first 5 injections made in 3-4 days, after 2 week break, another 5 injections 1 every 5-7 days), this is a basic course, then 3-6 months later a second course of 5 injections once in 7-14 days.

Topically to lubricate sores herpes used aniline dyes (fukortsin Zelenka), antiviral agents (acyclovir, zovirax, alpenarena ointment oxolinic ointment (remember that it stains the skin and clothing in blue!), tebrofenovuyu ointment, etc.), at the beginning of the disease are used in pill form acyclovir, or valtrex under the scheme, they also use immunomodulatory (agents that stimulate the immune system), eg. Interferon, Amiksin, Cycloferon, Neovir, Panavir, Polyoxidonium, Viferon, Kippered, etc.

During an exacerbation, it is desirable to limit the intake of bakery products and cereals (Kashi) containing arginine (amino acid).

It is advisable to take Vitamins-B for a month.

Herpes “cold” on the lips

The disease manifests itself by sores in the nose, lips and other parts of the face. Herpes on the lips mainly caused by the herpes simplex virus type I (HSV-I). 95% of people in the body the virus is present.

In rare cases, the cause of cold sores – the herpes simplex virus type 2 (transmitted through oral sex).
Herpes simplex virus that causes “cold” on the lips, stays inside the human body for life. Not currently developed drugs that were completely destroyed by the herpes simplex virus in the human body.

Up to 10 000 000 Americans annually suffer from “cold” on the lips . Approximately every 5 Europeans and Americans gets cold sores from 2 to 10 times a year. And only about 5% of the human race has immunity to HSV-I, the causes of which are still unclear.

The virus enters the body in early childhood: 3 to 4 years, when depleted of antibodies against the herpes virus transmitted to the infant by the mother. Most often, the infection occurs when the child kiss the infection carriers (parents, brothers, sisters and other relatives). In a kiss, the virus can enter the body together with the body fluids of others, for example, with saliva.

The virus is embedded in mucous, comes to the nerve endings, fluid flow, nourishing the nerves, up in the cranial cavity, where it “hides” in nerve plexus called the trigeminal ganglion, and sleeps there until re-activation. Thus, symptoms of herpes are not apparent immediately and the exact time of infection cannot be determined.

Reactivation of the virus is possible in the moment when the immunity is low. “Reduction” of immunity may occur under the action of cold (hypothermia), flu, menstruation (in women), emotional disorders and stress, strong ultraviolet radiation, excessive alcohol consumption, stomach upset and fatigue.

Causes of relapses of herpes labialis:

  • Stress or emotional disorder;
  • Various somatic diseases, including colds, flu, diabetes, HIV;
  • Poisoning or intoxication;
  • the Use of alcohol, caffeine andSmoking;
  • Excessive ultraviolet irradiation;
  • Hypothermia or overheating;
  • the Arrival of menstruation;
  • Fatigue and exhaustion;
  • Inadequate nutrition (diet) or upset stomach
  • Other individual factors.

Causes of relapses of herpes labialisOnce activated, the virus through the nerves extending from the trigeminal ganglion is sent back to the skin. It is important to know that from the trigeminal plexus depart branches that Innervate the lips, oral mucosa, gums, skin on the ear lobe and part of the cheeks. In accordance with the waste nerves will settle down and lesion on the skin. As it passes through the nerve, the virus causes inflammation of the nerve tissue that causes pain along the nerve fiber.

In its development the cold sore goes stage IV:

I stage of herpes – tingling. At this time most people feel sick.

Before to appear “cold” on the lips, the skin at the corners of the mouth or the inner surface of the lips or tongue, or even around the face begins to itch. In the place where soon will develop a recurrence of herpes, be harbingers of disease: pain, tingling, tingling, itching. The skin over the site of a future relapse blushes.

Herpes can be prevented if at this stage, to use drugs on the basis of acyclovir.

If you suffer from severe itching, you can take an Aspirin or Paracetamol.

II stage of herpes – the stage of inflammation, starts with a small, painful blister that gradually increases in size. The bubble is tense and filled with a clear fluid, which later becomes cloudy.

III stage of herpes – the stage of ulceration. The bubble bursts, it will expire colorless liquid, Packed with billions of viral particles. In its place is formed sore. At this point, the sick person is very contagious because it allocates a huge amount of viral particles into the environment. Because of the pain and sores on the face of the person most annoying this stage.

IV stage of herpes. Over the sores crust is formed, if the damage which can cause pain and bleeding.

Herpes rash often located on the red border of the lips, but may be on the nose, cheeks, ears, forehead, in the mouth: the gums, inside of lips and cheeks.

Obey the rules of personal hygiene. “Cold” on the lips contagious! Always wash your hands with soap before and after touching the herpes sores, including after application of antiviral cream.

Don’t touch your eyes!(especially the woman at the time of applying makeup). Do not use saliva to moisten your contact lenses. Despite the itching and pain, you should not touch the skin, to kiss, especially with children, to use someone else’s lipstick or lend her, to smoke a cigarette for a friend (girlfriend). Do not attempt to remove the blisters and crusts, to avoid transmitting infection to other body parts or bacterial infection.

Abstain from oral sex! Oral sex during “cold” on the lips of the “active” partner can cause genital herpes from a partner, passively participating in oral sex. The herpes lips “active” partner may be transferred to the genitals of a partner, receiving affection.

If You have a cold on the lips – use individual utensils or a towel, do not drink from other people’s glasses.

Shingles (herpes on the body)

Another form of herpes herpes zoster (or tinea versicolor).

The disease is caused by the herpes virus, which causes chickenpox. Causes of exacerbation of the disease, the same as that for simpleherpes.

Symptoms of herpes zoster

When opoyasyvaet herpes affects the skin and nervous system (this is due to severe pain during the disease).

The disease occurs more frequently in spring and autumn. Severe forms are more common in the elderly, children under 10 years of age rarely get sick, men are slightly more likely than women.

The skin lesions are often preceded by phenomena such as weakness, increased temperature body, malaise, headache, and neuralgic pain. Further reddened, swollen skin along the nerve, grouped vesicles appear, at first, they are transparent, but quickly become turbid (due to the mixing with blood, pus), they quickly opened with the formation of crusts, by the end of 2-3 weeks crusts fall off, in their place are dark spots, which will eventually pass. In most cases the disease is accompanied by swollen lymph nodes.

The symptoms of pain can be maintained for a long time (up to 6 months. and more) and after resolution of the disease, especially in elderly.

Treatment of shingles

The treatment of herpes zoster the same as that for simple herpes, additionally you need to consult a neurologist, additionally, use painkillers.

  • Genital herpes is manifested by itching and sores on the genitals. According to statistics in the world about 20% of people infected with genital herpes. 80% of them are not even aware of the presence of the virus in their body.the Genital herpes cause the herpes simplex viruses type I and II. In most cases – 80-85 % of genital herpes is caused by Iniusom PwomanGherpes type II (HSV-II). 15% – 20% of genital herpes caused by herpes virus type I (HSV-1).The proportion of patients with HSV – I is significantly increased in the last 10 years, which is likely related to the wide spread in society of oral-genital contacts: blow job and cunnilingus. Sometimes the cause of genital herpes can be a combination of 2 types of the virus: HSV-I and HSV-II.Herpes skin – occurs in people involved in the fight, Rugby and other sports where there is contact of the bodies. the Reason is the herpes virus type I. Manifested in the form of herpes rash on the head, neck, torso.Herpes of the eye – herpetic eye disease, is manifested by pain, photophobia, lacrimation. If time does not begin treatment, the patient may be decreased visual acuity, the lens become cloudy.

    Caring for a newborn, if you have herpes

    In order to avoid Contracting the herpes newborn, women who have cold sores on the lips before touching the child should wash hands thoroughly. If your lips are blisters or sores during child care use disposable surgical mask or gauze until then, until the sores will dry up. During a cold on the lips is not worth kissing or sniffing babe. If herpes is available on any other body part, it must be carefully closed and in any case not contact the skin of the child.