Peptic ulcer disease is a chronic disease, based on ulcer of the stomach or duodenum.
As a rule, ulcer occurs on the background of gastritis (inflammation of the mucous membrane of the stomach) or duodenitis (inflammation of the mucous membrane of the duodenum) associated with infection (Helicobacter pylori). Peptic ulcer disease is common in people of any age, but most often at the age of 30-40 years, men suffer 6-7 times more often than women.
Reasons for stomach ulcers
Damage to the mucosa with ulceration, erosions and inflammation associated with the prevalence of factors of aggression (hydrochloric acid, pepsin, bile acids) on the protective factors of the mucosa. An important role is infection with Helicobacter pylori. These microorganisms can cause inflammation of mucous membranes, destroying local protective factors and increasing acidity.
Factors contributing to the emergence of the disease include:
- long-term neuro-emotional stress;
- genetic predisposition;
- the presence of chronic gastritis or duodenitis;
- violation-mode power supply;
- the consumption of alcoholic beverages and Smoking;
- the use of some drugs (acetylsalicylic acid, indomethacin and others).
Symptoms of peptic ulcer disease
The most typical manifestation of peptic ulcer is pain in the upper abdomen that often occurs on an empty stomach, i.e., between meals. Pain may occur at night, causing the patient to Wake up and eat. The pain usually subsides within the first 30 minutes after a meal. Less specific but common case of peptic ulcer disease symptoms are nausea, heaviness after meals, feeling of fullness in the stomach, vomiting, decreased appetite, body weight, heartburn.
- Perforation of the ulcer is the formation of holes in the wall of the stomach or duodenum. This is one of the most dangerous complications of peptic ulcer disease, because it leads to getting the contents of the gastrointestinal tract into the abdominal cavity and infection of the abdominal cavity.
- Bleeding is usually manifested by staining chair in black color (blood passing through the gastro-intestinal tract is oxidized and becomes black).
- Malignancy transformation ulcers in a malignant tumor.
Complications of peptic ulcer disease is a series of life-threatening diseases, you should be aware of any patient with peptic ulcer disease.That is why one should never delay the treatment of ulcers and to discontinue therapy.
The main task of the patient is the adherence to diet and neat doctor’s prescriptions. The basis of therapeutic diet is chemical, mechanical and thermal sparing of the affected organ. Exclude products that increase gastric secretion (acute, pickled, salted, fried, smoked products, alcoholic beverages, coffee, tea, carbonated drinks, nourishing broths). Do not eat very hot or cold food. Smokers are advised to stop Smoking, because experts conclusively proven that Smoking is not only hinders the healing (lengthens treatment time), but also increases the risk of a relapse (recurrence of ulcers. Patients with ulcers should avoid taking aspirin, non-steroidal anti-inflammatory drugs.
Stomach ulcer Treatment in hospital
- radiography of abdominal cavity.
- fibroesofagogastroduodenoscopia. Endoscopic examination confirms the presence of the ulcer, specify its location, depth, shape, dimensions, allows to evaluate the condition of the bottom and the edges of ulcers, identify related changes of the mucosa. Faggs makes it possible to take a biopsy of the wall of the affected organ, with subsequent histological examination of the material obtained to exclude malignant nature of the lesion.
- pH meter – the study of acid-forming function of the stomach.
- fecal occult blood (for the diagnosis of possible bleeding).
research on infection (breath test, detection of serum antibodies to Helicobacter pylori, microbial inoculation taken at faggs material).
Drug therapy of peptic ulcer necessarily includes the preparations reducing secretion of hydrochloric acid in the stomach. If the ulcer is caused by infection with Helicobacter pylori eradication, the doctor will also prescribe antibiotic not less than 7 days.
Prevention of peptic ulcer disease
In order to prevent it is recommended:
- Measures aimed at the reduction of nervous tension;
- Smoking cessation and alcohol consumption;
- Normalization of the diet and the quality of the food;
- Treatment of chronic gastritis or gastro-duodenitis.