Toxocariasis is a zoonotic disease caused by parasitizing in humans roundworms of the genus Toxocara, which is often accompanied with damage to internal organs and eyes.
Most often affects children. Also found a relatively high prevalence of toxocariasis with certain professional groups (veterinarians, drivers and car mechanics, workers and utilities, gardeners). Important in the spread of toxocariasis have household insects, especially cockroaches.
Source of infestation for humans are dogs, polluting the soil with Toxocara ova, which are excreted in the faeces. Sick people are not the source of the infestation, because in their body the development cycle is incomplete (adult forms are not formed).
The disease occurs with pronounced allergic symptoms: itchy rash, fever, hepatosplenomegaly, pneumonia with painful bouts of coughing and breathlessness, puffiness of the face, the formation in various organs of specific granulomas containing larvae Toxocara.
Possible toxocarosis ophthalmic with lesions of the posterior segment of the eye (chorioretinitis), keratitis.
The mean duration of disease from several months to several years. Imaginal toxocariasis is rare. Clinically manifested by nausea, abdominal pain, profuse salivation, loss of appetite, dizziness.
Diagnosis is based on detection of antibodies to the antigen of larvae Toxocara in the reaction of indirect immunofluorescence, CFT, ELISA.
Apply tiabendazol (mintezol) 25-50 mg/kg of body weight per day in three divided doses for 5-10 days; ditrazin citrate 2-6 mg/kg 2-4 weeks. Good results are obtained when assignment of albendazole 10 mg/kg 10-20 days. It is also used vermox (mebendazole) at a dose of 100 mg 2 times a day for 1-4 weeks. In parallel is appointed desensitizing therapy.